Siddharth S. Matikonda, Ph.D.

20. H. Fukushima, A. Furusawa, S. Takao, S. S. Matikonda, M. Kano, S. Okuyama, H. Yamamoto, P. L. Choyke, M. J. Schnermann, H. Kobayashi, Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells, Ebiomedicine 102 (2024).

19. L. Lapoot, C. Wang, S. S. Matikonda, M. J. Schnermann, A. Greer, Bluer Phototruncation: Retro-Diels–Alder of Heptamethine Cyanine to Trimethine Cyanine through an Allene Hydroperoxide Intermediate, J. Org. Chem. 88 (24), 17430-17437.

18. A. Lawer, C. Tyler, K. Hards, L. M. Keighley, C. Cheung, F. Kierek, S. Su, S. S. Matikonda, T. McInnes, J. Tyndall, K. L. Krause, G. M. Cook, A. B. Gamble, Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase, ACS Med. Chem. Lett., 13 (10), 1663-1669. 

17. S. S. Matikonda, R. McLaughlin, P. Shrestha, C. Lipshultz, M. J. Schnermann, Structure-Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold, Bioconjugate Chem. 2022, 33, 7, 1241–1253.

18. H. Fukushima, S. S. Matikonda (co-first author), S. M. Usama, A. Furusawa, T. Kato, L. Štacková, P. Klán, H. Kobayashi, M. J. Schnermann, Cyanine Phototruncation Enables Spatiotemporal Cell Labeling, J. Am. Chem. Soc. 2022, 144, 25, 11075.

15. H. Alimoradi, A. Thomas, D. D. B. Lyth, A. B. Fallah, S. S. Matikonda, A. B. Gamble, G. Giles, SMA-BmobaSNO: an Intelligent Photoresponsive Nitric Oxide Releasing Polymer for Drug Nanoencapsulation and Targeted Delivery, Nanotechnology, 2022, 33, 195101.

14. H. Daly, S. S. Matikonda, J. Ivanic, M. J. Schnermann, Ketone Incorporation Extends the Emission Properties of the Xanthene Scaffold Beyond 1000 nm, Photobiology and Photochemistry, 2021:1-9.

13. P. Eiring, R. McLaughlin, S. S. Matikonda (co-first-author), Z. Han, L. Grabenhorst, D. A. Helmerich, M. Meub, G. Beliu , M. P. Luciano, V. Bandi, N. Zijlstra, Z. Shi, R. Swenson, P. Tinnefeld, V. Glembockyte, T. Cordes, M. Sauer, M. J. Schnermann, Targetable Conformationally Restricted Cyanines Enable Photon-Count Limited Applications. Angewandte Chemie, 2021, 60, 26685.

12. S. S. Matikonda, D. A. Helmerich, M. Meub, G. Beliu, P. Kollmannsberger, A. Greer, M. Sauer, M. J. Schnermann, Defining the Basis of Cyanine Phototruncation Enables a New Approach to Single Molecule Localization Microscopy, ACS Cent. Sci. 2021, 7, 7, 1144–1155.

*Highlighted in 2021, June,15 online edition of c&en news

11. D. A. Helmerich, G. Beliu, S. S. Matikonda, M. J. Schnermann and M. Sauer " Photobluing of organic dyes can cause artifacts in super-resolution microscopy", Nature Meth., 2021, 18, 253-257.

*Highlighted in EurekAlert! by the American Association for the Advancement of Science (AAAS)

10. S.S. Matikonda, J. Ivanic, M. Gomez, G. Hammersley, M. J. Schnermann, Core Remodeling Leads to Long Wavelength Fluoro-Coumarins, Chem. Sci. (Advance Article).

*Included in the 2020 Chemical Science HOT article collection

9.    S.S. Matikonda, G. Hammersley, N. Kumari, L. Grabenhorst, V. Glembockyte, P. Tinnefeld, J. Ivanic, M. Levitus, M. J. Schnermann “Defining the Impact of Cyanine Conformational Restraint in the Near-Infrared Range”, J. Org. Chem. 2020, 85, 9, 5907-5915
8.    S. S. Matikonda, J. M. Fairhall, F. Feidler, R. A. J. Tucker, S. Hook, A. L. Garden, A. B. Gamble “Mechanistic Evaluation of Bioorthogonal Decaging with trans-Cyclooctene: The Effect of Fluorine Substituents on Aryl Azide Reactivity and Decaging from the 1,2,3-Triazoline”, Bioconj. Chem., 2018, 29 (2), pp 324–334
7.    S. S. Matikonda, J. M. Fairhall, J. D. A. Tyndall, S. Hook, A. B. Gamble “Stability, Kinetic, and Mechanistic Investigation of 1,8-Self-Immolative Cinnamyl Ether Spacers for Controlled Release of Phenols and Generation of Resonance and Inductively Stabilized Methides”, Org. lett., 19 (3), 528–531
6.    H. Alimoradi, S. S. Matikonda, A. B. Gamble, G. I. Giles, K. Griesh “Hypoxia responsive drug delivery systems in tumor therapy”, Curr. Pharm. Des., 2016, 22(19), 2808-20
5.    S. S. Matikonda, D. L. Orsi, V. Staudacher, I. A. Jenkins, F. Fiedler, J. Chen, A. B. Gamble “Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition”, Chem. Sci., 2015, 6, 1212-1218
4.    M. H. Yang, S. S. Matikonda, R. A. Altman “Preparation of Fluoroalkenes via the Shapiro Reaction: Direct Access to Fluorinated Peptidomimetics”, Org. Lett., 2013, 15 (15), 3894–3897

*Highlighted in 2013 (vol 91, issue 32) edition of c&en news
3.    V.U. Jeankumar, R. Alokam, J. P. Sridevi, P. Suryadevara, S. S. Matikonda, S. Peddi, S. Sahithi, M. Alvala, P. Yogeeswari, D. Sriram “Discovery and structure optimization of a series of isatin derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors”, Chem. Biol. Drug Des. 2014, 83(4), 498-506
2.    R. Alokam, V. U. Jeankumar, J. P. Sridevi, S. S. Matikonda, S. Peddi, M. Alvala, P. Yogeeswari, D. Sriram “Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors”, J. Enz. Inhib. Med. Chem., 2014, 29(4), 547-54
1.    P. Yogeeswari, S. K. Patel, I. V. Reddy, A. Semwal, M. Sharma, M. Gangadhar, S. S. Matikonda, S. Dharmarajan “GABA derivatives for the treatment of epilepsy and neuropathic pain: A synthetic integration of GABA in 1, 2, 4–Triazolo–2H–one nucleus”, Biomed. & Aging Path., 2012, 2(2), 31–40